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Gao agreed that the diagnosis of restless legs syndrome is not as straightforward as other diagnoses, and that some of the men who reported restless legs syndrome probably did not really have it.
Using certain prescription or illegal drugs can suggest a chemical cause, since drug effects account for 25 percent of ED cases. Cutting back on or substituting certain medications can often alleviate the problem.
Prostatitis can cause pain and discomfort during and after ejaculation and plays a role in erectile dysfunction.
Reprints: Dr. Setter, Department of Pharmacotherapy, College of Pharmacy, Washington State University/Elder Services, 5125 N. Market St., Spokane, WA 99217-6131, fax 509/458-7459, ssetter@smhca.org
"Having an erection does not mean you are being sexual. Being sexual comes from inside your sense of yourself," Shaw says. "You can be sexual, you can feel sexual, you can behave sexually without an erection. A penis is not the only part of a man's body that can be used sexually."
Objective To assess the efficacy and safety of oral sildenafil citrate in the treatment of erectile dysfunction in men with diabetes.
Figure 5. Sildenafil down-regulates IL-4R expression on CD11b+ cells. CD4+, CD8+, CD11b+, or CD11c+ cells were magnetically purified from spleens of C26GM-bearing mice challenged 9 d earlier. CD4+ or CD8+ T cells were stimulated with ConA for 3 d, with or without 50 µg/ml sildenafil. (A) Purified cells were cultured separately for 2 d with or without sildenafil, harvested, and used to determine cGMP levels, as described in Materials and methods. (B) T cell proliferation was determined by [3H]thymidine incorporation. (C) CD11c+ cells were analyzed for B7.2 and MHC class II expression. (D) CD11b+ cells were analyzed for IL-4R expression by flow cytometry. The t test p-value is reported. Error bar values are shown. MFI, multiplicity of infection.
The findings were published in this week's Proceedings of the National Academy of Sciences.
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